Save the Date: Dueling Endocrinologists Discussing Hypothyroidism Diagnosis and treatment: Commonalities and Differences

 

  • Dr. Friedman will be joined by Brittany Henderson, MD, ECNU for an exciting GoodHormoneHeath Webinar on Dueling Academic-Based Endocrinologists discussing state-of-the-art hypothyroidism diagnosis and treatment: Commonalities and Differences

    Each expert will discuss the following topics:

  • How is mild hypothyroidism diagnosed?
  • Why are full thyroid panels and not just TSH needed?
  • What is the role of rT3?
  • How to optimally use all types of thyroid hormone including NDT
  • Why both conventional and alternative providers have it wrong?
  • They will briefly discuss the proposed ban on desiccated thyroid by the FDA.

Sunday • September 14• 5 PM PDT/ 8 PM EDT
Via Zoom Click here to join the meeting or
https://us06web.zoom.us/j/4209687343?omn=87459672811
OR
16694449171,,4209687343#
Slides and copy of the paper and the press release will be available before the webinar and recording after the meeting at slides
OR
Join on Facebook Live – https://www.facebook.com/goodhormonehealth at 5 PMPDT/ 8 PM EDT

Your phone/computer will be muted on entry. There will be plenty of time for questions using the chat button.

Research Study for Patients Diagnosed with Cushing’s Disease and Their Caregivers

We’re looking for caregivers to loved ones diagnosed with Cushing’s Disease or patients diagnosed with Cushing’s Disease to participate in a research study.

✅ Who: Patients and caregivers of loved ones

⏳ What: 30-minute Online Survey

💰 Compensation: $60.00

Sign up here: https://rarepatientvoice.com/CushingsHelp/

 

Hypercoagulability in Cushing Syndrome

Introduction

Cushing syndrome is a prevalent endocrine disorder that impacts multiple bodily systems. Although 80% of patients have ACTH-dependent Cushing syndrome (typically caused by Cushing disease), around 20% of ACTH-independent CS are noted mostly due to adrenal adenoma. Patients with this condition have an approximately 8% risk of thromboembolism. This hypercoagulable state is thought to result from the activation of the coagulation cascade, along with impaired fibrinolysis and prolonged clot lysis time. Vigilance in recognizing and managing these complications is essential to improving patient outcomes.

Section snippets

Case Report

A 44-year-old woman with a medical history of type 2 diabetes mellitus, obesity, and tobacco dependence presented to the clinic for obesity management. She had been started on weight loss medication, but there was minimal improvement in her condition. The patient denied using steroids or oral contraceptive pills and reported well-controlled diabetes. Due to the lack of progress, an extensive workup was conducted, revealing the following: an am cortisol of 2.4 mcg/dL after 1 mg of dexamethasone

Case Report

Few days later, she was admitted to the emergency department with acute hypoxia, requiring up to 6 L of oxygen via nasal cannula, and severe abdominal pain. A CT scan of the chest, abdomen, and pelvis revealed a right renal infarct, a splenic infarct, and a pulmonary embolism. A venous duplex of the left lower extremity was negative for deep vein thrombosis, and hypercoagulable workup was also negative. An echocardiogram identified a patent foramen ovale, which was repaired, and she was started

Discussion

This case highlights the necessity of providers to be aware of potential complications of endocrinological disorders. The risk of thromboembolism is more commonly present in patients with Cushing syndrome, who have risk factors such as obesity, surgery and invasive diagnostic procedures. Patients should be treated as having a prothrombotic disorder and undergo antithrombotic prophylaxis following procedures. The risk of thromboembolism in patients with Cushing syndrome should be widely

Conclusion

This case highlights the necessity of providers to be aware of potential complications of endocrinological disorders. The risk of thromboembolism is more commonly present in patients with Cushing syndrome, who have risk factors such as obesity, surgery and invasive diagnostic procedures. Patients should be treated as having a prothrombotic disorder and undergo antithrombotic prophylaxis following procedures. The risk of thromboembolism in patients with Cushing syndrome should be widely

A Rare Case of Hypercortisolemia Alongside Anorexia Nervosa

Cushing’s: A Comprehensive Guide to Understanding a Devastating Condition

 

This book is perhaps something a little different than most would expect. Firstly, it’s a single-author book on Cushing’s syndrome. It is not, like most textbooks, a compendium of edited submissions from multiple authors where there are often divergent opinions from one chapter to the next. Instead, it’s a treatise reflecting my education and experience. It is not referenced but instead each chapter is followed by suggested readings. It represents my thoughts, understanding and a personal reflection on a career of evaluating a multitude of patients suspected of having the disorder and treating those confirmed to have hypercortisolism due to one cause or another. It reflects my perspectives of the art and science of the field.

In this book you’ll find my personal opinions about all matters from diagnostic testing to approaches to management. I share patient stories that are particularly informative and indicate how I learned from those patients and built on the foundation of my knowledge to take better care of subsequent patients. I relate scientific information, and results of studies, and comment on the utility and practicality of these results. While you are reading, you might learn a thing or two about statistics. I also relate some of the general essentials of the “art of medicine” that I have learned not only from professors I had encountered in my training and education, but also from my patients and colleagues as well as my nursing and administrative colleagues.

I trained in the era of what I like to think of as the modern-day Renaissance of “evidence-based medicine.” This approach dramatically changed the face of medicine, the doctor-patient relationship, and even the influence of third-party payors and government entities. Unfortunately, however, much of the art of medicine has been seemingly deemed less important that data mining and interpretation. I firmly believe that most physicians can acquire the skills and attitudes required to practice medicine with artful expression while incorporating evidenced-based recommendations. Much of this book illustrates an approach to using data and knowledge with experience to formulate action plans for the benefit of patients. I don’t think of the approaches I share as unconventional, but they may be unfamiliar to those who practice with an emphasis on evidenced-based medicine and who have not seen a lot of patients with the set of disorders leading to Cushing syndrome.

I think of the art and science of our craft as the foundation of what we now call “medical decision-making.” So many different factors need to be considered to make the right choices about diagnosis and treatment of diseases. Medical decision-making implies that one looks at all the evidence and facts about a patient, with an understanding of the applicable scientific evidence of medicine, and then utilize one’s experience to make several decisions, including whether a diagnosis is present or absent, the need for further diagnostic studies, and the best approach to treatment.

This approach should treat patients as individuals, according to need based on a multitude of assessments. I have often said, that if you show me 100 patients with Cushing’s disease, all with the same duration of the condition, identical biochemistry, and tumor sizes, you will show me 100 different illnesses. Everybody is different and I relate some examples in this book. Every patient deserves to be treated as an individual. This is where guidelines fail both physicians and patients. They try to fit square pegs into round holes where all patients are treated equally or according to a formulaic approach rather than according to individual needs. I suggest that physicians use their minds to devise an evaluation and management plan rather than defaulting to and following a guideline. If you’re unable to do so, then you probably should refer the patient to an expert.

On Amazon.