Abstract
This report discusses a misdiagnosed case of CD in a 42-year-old obese male with hypertension. CD was suspected only after surgery, confirmed by magnetic resonance imaging (MRI) showing a pituitary macroadenoma.
Despite transsphenoidal surgery and ketoconazole therapy, the patient suffered liver failure and died.
Among 20 CD reviewed cases in the literature, 65% were misdiagnosed. MRI and immunohistochemistry confirmed tumors, with 55% achieving remission post-surgery. Screening for CD before bariatric surgery may prevent mismanagement and complications.
Read more at https://academic.oup.com/jscr/article/2025/6/rjaf366/8158339?login=false
Filed under: Cushing's, pituitary, Treatments | Tagged: bariatric surgery, Cushing's Disease, ketoconazole, liver failure, obesity, Pituitary adenoma, Transsphenoidal surgery | Leave a comment »
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