CushieBlog

Cushing’s Help RSS Feed

• ⁉️ Cushing's Survey
  One survey is for people who are undiagnosed but currently seeking diagnosis, the other is for people who have been diagnosed and treated. Please take these quick surveys. I'm hoping that by incorporating these statistics into my paper I can make a valid argument and help raise awareness for all of us.
• 🖊 Courtnay P (Courtnay), Undiagnosed Bio
  Courtnay is from Canada. She thinks she has Cushing's Disease caused by a pituitary tumor but doctors won't send her for an MRI.
• 📰 Long-acting pasireotide safe, effective for recurrent Cushing’s disease
  “Surgical resection of the causative pituitary adenoma is the first-line treatment of choice for most patients with Cushing’s disease, which leads to remission in greater than 75% of patients if done by an expert pituitary surgeon,” Andre Lacroix, MD, professor in the department of medicine at University of Montreal teaching hospital, and colleagues wrote in […]
• 📰 New ACTH Detection Method Improves Cure Rates in Cushing’s Disease Patients
  MRI, for example, detects only 50 percent of Cushing’s adenomas, limiting surgeons’ ability to conduct curative TSR surgeries. Therefore, better diagnostic and tumor localization techniques are needed to increase the likelihood that initial surgeries can remove the entire tumor and cure patients.
• 📰 Intraoperative MRI improves complete resection of pituitary macroadenoma
  The use of intraoperative MRI, especially with transsphenoidal reoperations for invasive and noninvasive pituitary macroadenomas, leads to significantly higher “gross tumor resection” rates. This method prevents additional operations or treatment, such as radiation, because it reduces the number of patients with residual adenoma after surgery. This technolog […]
• 📰 Blood Sample from Tributary Adrenal Gland Veins May Help to Diagnose Subclinical Cushing’s Syndrome
  Researchers report a new technique for collecting blood samples from tiny veins of the adrenal glands, called super-selective adrenal venous sampling (ssAVS). The technique can be used to help diagnose diseases marked by excessive release of adrenal hormones, such as subclinical Cushing’s syndrome (SCS) or primary aldesteronism (PA).
• 🖊 Cathy T, Pituitary Bio
  Cathy is from Wellington, New Zealand and had the left side of her pituitary gland removed and a BLA. Cathy has been through 2 cycles of IVF fertility treatment and the second one worked. She had a baby girl. Cathy updated her bio in September 2009. She has another new 5mm tumour on the right side of her pituitary gland. She has Nelsons Syndrome and Addison […]
• ✈️ Adventures with Human Growth Hormone: Travelling (Flying)
  I had the gel pack from the iCool frozen solid and put that in a small Rubbermaid lunch bag with 2 thin ice packs,  1 on top and 1 on the bottom.  If you don't want to read all the way to the end, this system kept the growth hormone cold for the 20 hours going and returning but the 2 thin blocks had completely thawed.  The inner iCool was mostly frozen […]
• 🖤 In Memory: Martha, October 14, 2008
  StaceyH wrote: Dr. F had wanted to give Martha an IPSS, but she had a problem with an EKG two weeks ago so the doctor would not release her for surgery. She went for a cardio stress test last week and was to get her results tomorrow. She was feeling “ok” but when I arrived home this evening, I found her in the bathroom. I tried to give her CPR but I really k […]
• 📰 Low-dose Steroids Relieve Sore Throat Pain
  NEW YORK (Reuters Health) – A single low dose of corticosteroids speeds pain relief in patients who have sore throat, without serious adverse effects, according to a systematic review and meta-analysis published in The BMJ along with parallel clinical practice guidelines. “The relative effects were similar across severities, though patients with less severe […]
• ⁉️ Would *You* Do This?
  The case report described a woman who was admitted to a specialist clinic after two endocrinologists had failed to diagnose what they suspected was cyclic Cushing’s syndrome. The woman had complained of fatigue and weight gain over the past four years despite weight loss banding surgery, and declined taking steroid medications. The examination did not reveal […]
• 📰 Increase in Glucose Uptake by Cushing’s Disease-associated Tumors Could Improve Early Detection
  Microadenomas – tumors in the pituitary gland measuring less than 10 mm in diameter – that release corticotropin, or  corticotropinomas, can lead to Cushing’s disease. The presurgical detection of these microadenomas could improve surgical outcomes in patients with Cushing’s.
• ‼️Pituitary Post-Op
  After Your Transsphenoidal (Pituitary) Surgery After your physicians have determined that it is reasonably safe to discharge you from the hospital following transsphenoidal pituitary surgery there are a number of important situations that may arise. Most people feel well after discharge. However, you should be aware of these possible problems, just in case. […]
• 📰 Addison's Disease: Periods at 4 years, Menopause at 5
  In addition to Addison’s disease, Emily has been diagnosed with congenital Adrenal Hyperplasia, Central Precocious Puberty, Autism Spectrum Disorder, Sensory Processing disorder and Anxiety Disorder. The 5-year-old’s adrenal glands don’t produce enough steroid hormones.
• 🖤 In Memory: Bonny Hamm, October 12, 2009
  Bonny was only 45 at the time of her death October 12, 2009. She had had her left Adrenal Gland and its tumor removed in June 2007.
• ✍️ Comment added to Alex C (Alex C), Undiagnosed Bio
  Hi Alex I am a specialist in rare disease and you need to find yourself a good endocrinologist that will take screening for Cushing’s seriously. Demand an overnight Dexamethasone suppression test to start. Ask to get both a cortisol level in addition to the Dexamethasone level...
• 🖤 In Memory: Barbara "Cookie" Rothenberg, October 11, 2003
  Cookie died October 11, 2003. She had a pituitary tumor, recurrence, BLA, PCOS, radiation... Cookie touched a lot of lives. I would get these perky, cheerful and witty emails. It is terrible to lose her. She has left such a legacy, though, that she will go on touching lives for many years to come. She loved people and wanted to make a difference in the lives […]
• 📰 Cortisol Modulator Shows Early Signs of Safety, Efficacy in Healthy Volunteers
  “This first-in-human study has demonstrated that CORT125134 is well tolerated following single doses up to 500 mg and repeated doses up to 250 mg once daily for 14 days,” researchers wrote. “Pharmacological activity was confirmed following the administration of a single 500-mg dose and daily administration of 250 mg.”
• 📰 Cushing’s Syndrome Revealing Carney Complex: A Case Report
  We report a case of a 35-year-old patient diagnosed with Cushing’s syndrome complicated with an impaired glucose tolerance (IGT) and a severe psychiatric disturbance. The diagnosis of CNC was made by having two major criteria, namely a primary pigmented nodular adrenal disease (PPNAD) and thyroid carcinoma.
• 🖤 In Memory: Edward H. Oldfield, MD, 1947–2017
  Dr. Oldfield was my pituitary surgeon at NIH back in 1987. He saved my life. Ed started as Senior Staff Fellow in the Surgical Neurology Branch at the NIH (1981). After 5 years, Ed would become the Chief of the Surgical Neurology Branch. He would stay on as Branch Chief and lead the neurosurgical effort at the NIH for the next 21 years. During his tenure, he […]