AT ICE/ENDO 2014
CHICAGO – Late-night salivary cortisol exceeded normal limits in 10 women with recurrent Cushing’s disease a mean of 3.5 years after transsphenoidal surgery, but their urinary free cortisol remained in normal limits, according to a retrospective review from the Medical College of Wisconsin, Milwaukee.
That adds strength to the notion that late-night salivary cortisol (LNSC) catches recurrent Cushing’s that’s missed by urinary free cortisol, even though UFC remains a standard screening approach in some places.
The study is tiny and retrospective, but at the joint meeting of the International Congress of Endocrinology and the Endocrine Society, lead investigator Dr. Ty Carroll explained why the findings still matter, and also why two LNSC measurements are better than one.
Filed under: Clinical trials, Cushing's, Meetings and Conferences, pituitary, Rare Diseases | Tagged: Cushing's, Cushing's Disease, Cyclical Cushing's, Dr. Ty Carroll, ICE/ENDO 2014, late-night, late-night salivary cortisol, LNSC, Medical College of Wisconsin, salivary cortisol, study, transsphenoidal, UFC, urinary free cortisol, video |
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