Hollywood actor, 42, is trapped in a 14-year-old body and loves it

Mario Bosco’s memoir entitled ‘From Hopeless to Hollywood: The Mario Bosco Story,’ which came out in July, details how his condition that makes him small helped him to land a Hollywood career.

He spent his childhood being bullied by his peers for his small frame and as he was shuffled from hospital to hospital he sometimes wanted to die.

But now, Mario Bosco, 42, of Brooklyn, New York is a Hollywood actor and author whose rare illness that makes him look like a 14-year-old boy is the very thing that fuels his impressive career.

Bosco’s memoir entitled ‘From Hopeless to Hollywood: The Mario Bosco Story,’ which came out in July, details how panhypopituitarism, a condition caused by damage to his pituitary gland at birth, gave him the chance to play children on TV and in movies.

‘Life is tough but tomorrow is a surprise. Your dream is your friend and you have to believe in it to make it happen,’ Bosco told Dailymail.com of overcoming adversity to fulfill his lifelong dream of becoming an actor and writer.

Read the whole article here: Hollywood actor, 42, is trapped in a 14-year-old body and loves it

Cushing’s Syndrome

The Seven Dwarves of Cushing's


Posted Oct. 1st, 2015 by

Q: Would you please explain Cushing’s disease. How is it diagnosed? What are the symptoms?

A: Cushing syndrome results from excess levels of the hormone cortisol. It is produced in various glands, usually the adrenal that is situated above the kidneys on both sides, and the pituitary gland, which is in the centre of the brain.

Cortisol also regulates the way fats, carbohydrates and proteins are turned into usable forms of energy. These glands produce other hormones that affect things such as blood pressure and the body’s response to stress.

Cortisol may be added from outside the body by taking medications such as prednisone, often used for the control of chronic inflammatory or autoimmune diseases like lupus or rheumatoid arthritis.

Prednisone is also used for the treatment of acute illnesses such as severe allergies. Poison ivy is often treated this way.

Women in the last three months of pregnancy also have increased blood levels of cortisol and may temporarily display some of symptoms of Cushing’s syndrome.

Any problem with the pituitary gland, the nearby hypothalamus in the brain or adrenals can lead to Cushing’s syndrome. The most common is a benign tumour of the pituitary gland known as a pituitary adenoma.

This type of tumour may produce an excessive amount of a stimulating hormone known as ACTH, which in turn activates the hormones in the adrenal glands. On rare occasions, some types of lung or thyroid cancer can also behave in a similar way.

The most obvious sign of Cushing’s disease is marked weight gain, mostly in the abdomen, face and neck, while the arms and legs remain relatively thin.

As the skin in these areas becomes thinner, there may be purple coloured stripes or stretch marks. Women may also lose their periods and grow facial or body hair.

Blood pressure is usually high and sufferers feel weak and tired.

Cushing’s disease is diagnosed by measuring the amount of cortisol in a person’s urine during a 24 hour period.

If there is a tumour it will require surgical removal. If Cushing’s syndrome is a result of prescribed medication, the dosage can be reduced gradually or another type of medication can be tried. Prednisone must never be suddenly discontinued or the person’s blood pressure could drop dramatically, which could be serious and potentially fatal.

Clare Rowson is a retired medical doctor in Belleville, Ont. Contact: health@producer.com

From http://www.producer.com/2015/10/cushings-syndrome/

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