Comment from LinkedIn: Congratulations Mary! You have helped more lives than you will ever know including mine. I am forever grateful for finding your website 18 years ago when I was finally diagnosed with Cushings Disease after a 2-year search for answers. Thank you 😊
Today is the birthday, or anniversary, of the boards starting September 30, 2000 (The rest of the site started earlier that year on July 21, 2000) As of today, we have 73,024 members who have made countless posts.
Bettye passed away due to complications of Cushing’s disease. Once she was finally diagnosed, a decision was made against surgery and Bettye was put on the cortisol-lowering medication Korlym. Though she had initially gained weight from Cushing’s disease, as many patients do, she rapidly lost weight and was admitted into hospice care soon after.
Joanne was known on the boards as raggettyjoanne. Mario VandDermeij announced the passing of his loving wife of 23 years. Joanne Swain VanDermeij at the age of 56. After 2 years and 3 months of fighting the system, Joanne was finally diagnosed March the 14th, 2011, with full blown adrenal Cushing's.
The FDA on Friday approved Recordati's Isturisa (osilodrostat) to treat Cushing's disease—a rare disease in which patients' adrenal glands produce too much cortisol—in those who have undergone a prior pituitary gland surgery or are not eligible for one.
Patients with suspected adrenocortical carcinoma (ACC) may also undergo additional tests to identify excess sex steroids and steroid precursors, mineralocorticoids and glucocorticoids.
Mutations in the two Cushing’s disease mutational hotspots USP8 and USP48 are less frequent in corticotroph macroadenomas and invasive tumors. There is evidence that TP53 mutations are not as rare as previously thought in these tumors.
More than 80% of adults with Cushing’s disease receiving osilodrostat had normalized mean urinary free cortisol levels at 72 weeks of treatment, according to findings from the LINC 3 study extension.
Version 4.7.1 This is our September maintenance release. Key Changes include: Improved search bar UI. New ability for topics to be published on a future date.
“In general, cortisol levels tend to peak in the late morning and gradually decline throughout the day,” he explains. “When a stressful event occurs, the increased cortisol will work alongside our ‘fight or flight’ mechanisms to either upregulate or downregulate bodily functions. [Affected systems include] the central nervous system, cardiovascular system, g […]
I have many symptoms of cushings, I have used cloatasol propionate for about 5 years for my chronic eczema I was on oral steroids in July then high dose steroids again in September. thejuly in July it was for a severe eczema breakout and in September it was for sudden hearing loss. Now I need a hearing aid. I seen one place after googling that connects cushi […]
Cushing’s syndrome (CS) is a rare condition of chronically elevated cortisol levels resulting in diverse comorbidities, many of which endure beyond successful treatment affecting the quality of life. Few data are available concerning patients’ experiences of diagnosis, care and persistent comorbidities.
We describe the first report of recurrent Cushing's Disease that was quiescent during pregnancy and diagnosed in the immediate postpartum period. Understanding the risk and mechanisms of CD recurrence in pregnancy allows us to counsel these otherwise healthy, reproductive-age women in the context of additional family planning.
Ryan passed away peacefully and is free from illness and pain....Also mourning his loss are aunts, uncles, cousins, many life-long friends and friends through Cushing's Disease Awareness.
In Memory of those we have lost. Janice died Tuesday, September 4, 2001. The very first Cushing's Awareness Ribbons were made for, and worn at, Janice's funeral. She had adrenal Cushing's.
English: “Dr. Harvey Cushing,” oil on canvas, by the American artist Edmund Tarbell. Courtesy of the Dittrick Medical History Center. (Photo credit: Wikipedia)
Synopsis: 36 year old male who presented with weight gain, proximal muscle weakness, and excessive sweating. Among multiple 24-hour urine free cortisol and midnight salivary tests, a minority were minimally elevated.
The diagnosis of Cushing’s disease was questioned over an eight month evaluation period.
The challenges of diagnosing Cushing’s disease are discussed.
CushieBlog 